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APC Forum – Diverse approaches to unravelling gut metabolism and the disease state

2.00pm     Prof Rinki Murphy, University of Auckland. 

Enhancing gut resilience to Obesity and Type 2 Diabetes.

2.45pm     Dr Eileen Ryan, University of Melbourne.

Current Mass Spectrometry Based Strategies for Elucidating the Lipidome

3.05pm     Seán O’Callaghan, University of Melbourne.

Omics as a service: a bioinformatics perspective

3.20  Q&A

3.30  Close


Speaker Biographies

Rinki Murphy is an endocrinologist visiting from New Zealand.  She is an Associate Professor in medicine at the University of Auckland, a member of the Healthier Lives Science Leadership Team and principal investigator for the Maurice Wilkins Centre for Molecular Biodiscovery a national Centre of Research Excellence.  Rinki’s research in diabetes and obesity spans basic molecular science, physiology, and clinical research, with membership of multiple national and international collaborations in several observational studies and clinical trials.

Eileen Ryan obtained her PhD in nutritional sciences from UCC under the supervision of Professor Nora O’Brien. She spent a year at UCC as a postdoctoral scientist and in 2008 took up a post at the Centre for Drug Candidate Optimisation (CDCO) based within Monash University, Australia. Here she spent several years working as a research officer with a focus on in vitro drug metabolism and mass spectrometry based identification and structural elucidation of drug metabolites. In 2014, she accepted a postdoctoral position with Professor Gavin Reid at the University of Melbourne. Since then her research has been focused on MS based lipid analysis (lipidomics), specifically on the development of novel MS based strategies for analysis of complex lipids and bioactive lipid mediators as well as the application of these methods toward understanding the role of lipids in the onset and progression of disease. Her research interests include lipidomics, biomarker discovery, metabolic pathways and nutritional biochemistry.

Seán O’Callaghan graduated with a B.E. in Electrical Engineering from UCC in 2004, and then worked as a research scientist at the Tyndall Institute in semiconductor device physics and the design and simulation of novel semiconductor devices. In 2010 he moved into the field of Bioinformatics, accepting a position at Metabolomics Australia (MA), an Australian Government initiative to accelerate the development of metabolomics in Australian science. At MA Seán led the development of the PyMS Gas Chromatography Mass Spectrometry (GC-MS) data analysis software package. Later he played a leading role in the development of fluxomics capabilities at MA, and the design, data processing and quality control of very large scale Liquid Chromatography Mass Spectrometry (LC-MS) experiments. In imaging mass spectrometry (IMS) he has worked with leaders in the field at the European Molecular Biology Laboratory to explore new ways of mining and visualizing IMS data. In August 2016 he accepted a position as Senior Bioinformatician at the Melbourne Mass Spectrometry and Proteomics Platform which provides mass spectrometry and proteomics to researchers all over Australia, and is backed by a cutting-edge suite of Mass Spectrometers including several Thermo-Fisher Scientific Orbitrap machines. Working closely with David Perkins, a noted leader in the field of Proteomics Bioinformatics, Seán leads development of the MSILE laboratory information management and data analysis system and provides bioinformatics guidance to the several hundred individual users of the platform.


Date/Time Date(s) - May 30 2017 2:00 pm - 3:30 pm

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UCC Lecture Theatre LG51 Cavanagh Pharmacy Building