Gut Instinct Science Series – Prof Mark Lyte
Prof Mark Lyte
Prof of Vet Microbiology & Preventive Medicine, Iowa State University
“The Role of Microbial Endocrinology in Health: From Infectious Disease to the Microbiota-Gut-Brain Axis”
Microbial endocrinology represents the intersection of two seemingly disparate fields, microbiology and neurobiology, and is based on the shared presence of neurochemicals that are exactly the same in the host as well as in the microorganism. The ability of microorganisms not only to respond to but also to produce many of the same neurochemicals that are produced by the host, such as during periods of stress, has led to this evolution-based mechanism being shown to have a role not only in the pathogenesis of infectious disease and homeostasis, but also in the ability of the gut microbiota to influence behavior through the microbiota-gut-brain axis. This may have particular relevance to the study of the mechanisms by which probiotics may function to influence behavior since probiotics are capable of the production of large quantities of neurochemicals. This talk will therefore focus on the application of a microbial endocrinology-based approach (one that is rooted in an evolutionary understanding of neurochemical-based communication) as a one of the mechanisms by which the microbiome interacts with its host in both disease progression and overall health).
Hosted by John Cryan
Date/Time Date(s) - Dec 21 2016 12:00 pm - 1:00 pm
UCC Cavanagh Pharmacy Building lecture theatre LG 51