John Cryan

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John F. Cryan – Principal Investigator


Tel: +353 21 4205426



1995     BSc Biochemistry,  National University of Ireland, Galway

1998     PhD Pharmacology, National University of Ireland, Galway

Career Profile:

John F. Cryan is Professor & Chair, Dept. of Anatomy & Neuroscience, University College Cork.  He received a B.Sc. (Hons) and PhD from the National University of Ireland, Galway, Ireland. He was a visiting fellow at the Dept Psychiatry, University of Melbourne, Australia (1997-1998), which was followed by postdoctoral fellowships  at the University of Pennsylvania, Philadelphia, USA and The Scripps Research Institute, La Jolla, California. He spent four years at the Novartis Institutes for BioMedical Research in Basel Switzerland, as a LabHead, Behavioural Pharmacology prior to joining UCC in 2005 where he was  a Senior Lecturer in Pharmacology in the School of Pharmacy and in the Dept. Pharmacology & Therapeutics UCC. He is a Principal Investigator in the APC Microbiome Institute.

Prof. Cryan has an H-Index of 57 (Google Scholar) having published over 250 peer-reviewed articles and book chapters including articles in high-impact journals such as PNASNeuronNature Reviews Neurosci. Molecular PsychiatryBiological Psychiatry,Progress in NeurobiologyNature Reviews Drug Discovery, GastroenterologyGut and Journal of Neuroscience. He  has edited books  on “Behavioural Neurogenetics” (Springer Press, 2012) on “Depression: From Psychopathology to Pharmacotherapy” (Karger Press, 2010)

and “Microbial Endocrinology: The Microbiota-Gut-Brain Axis in Health and Disease” (Springer Press, 2014).


Prof. Cryan was recently selected as a Highly Cited Researcher by Thomson Reuters.  Those researchers who, within an ESI-defined field, published Highly Cited Papers were judged to be influential, so the production of multiple top 1% papers was interpreted as a mark of exceptional impact.  Professor Cryan, as a member of the Highly Cited Researcher List is also included in the 2014 The World’s most Influential Scientific Minds

Prof. Cryan is a Senior Editor of Neuropharmacology and Nutritional Neuroscience and an Editor of British Journal of Pharmacology. He is Advisory Editor of Psychopharmacology; on the Board of Reviewing Editors of Brain Research; an Associate Editor of Frontiers in Behavioural Neuroscience; an Associate Editor of Frontiers in Psychopharmacology and Frontiers in Gastrointestinal Pharmacology; an Editorial Board Member of Behavioural Pharmacology; Neuroscience and Biobehavioral Reviews, Genes, Brain & Behavior and International Journal of Neuropsychopharmacology. Prof Cryan received the inaugural University College Cork Researcher of the Year Award in 2012. Cryan has also been honoured with the European College of Neuropsychopharmacology (ECNP) Fellowship Award, the Wyeth Psychopharmacology Award from British Association of Psychopharmacology and the Young Scientist Award from the European Behavioural Pharmacology Society. He has received commercialisation awards from UCC in 2012 and 2013. Further, in 2013 he received the University of Utrecht Award for Excellence in Pharmaceutical Research and delivered the Royal Academy of Medicine in Ireland Conway Review Lecture and the De Pazzi Lecture at University College Cork. He gave the Wingate Lecture at Barts & The London School of Medicine and Dentistry in 2014. Prof Cryan was also a TEDMED Invited Speaker in 2014.

Research Interests

Prof. Cryan’s current research interests include the neurobiological basis of stress-related neuropsychiatric disorders including depression, anxiety and drug dependence. Moreover, his group is also focused on understanding the interaction between brain, gut & microbiome and how it applies to stress and immune-related disorders, including irritable bowel syndrome and obesity and neurodevelopmental disorders such as autism. He is also interested in applying novel approaches to facilitate drug/siRNA delivery to the brain in vivo.

Prof. Cryan’s research group consists of 12 Postdoctoral Fellows, 14 PhD students, 2 MD students, 2 MSc Students, 3 research scientists and various visiting students from Ireland, Spain, The Netherlands, USA & Canada. It is funded by Science Foundation Ireland, the Health Research Board, Enterprise Ireland and the Irish Research Council. Moreover, Prof. Cryan receives funding as a PI on the two different EU Framework 7 Programme grants.

Professional activities:

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