Next Generation Sequencing

APC Microbiome Institute Sequencing Platform

The APC Microbiome Institutes state of the art DNA sequencing technology allows researchers to:

  • Accurately assess the composition or functional potential of the gut microbiota and microbiota of other environments (16S/ Shotgun metagenomic, RNAseq transcriptomics).
  • Assess the microbiota impact on health and disease.
  • Establish the impact of interventions (dietary, probiotic, prebiotic, antibiotic and/or chemotherapeutic) on these populations.
  • Decipher the associated health promoting mechanisms of action of specific health promoting strains.
  • Ensure the absence of virulence factors and assess the suitability of health-promoting strains for large scale industrial production.
  • Facilitate the sequencing of host eukaryote DNA with RNAseq being particularly advantageous.

The services that the Sequencing Platform offers to users are:

  • Project Design
  • Standard and Custom Library Generation
  • De Novo Sequencing of Genomes
  • Re-Sequencing of Genomes
  • Microbiome composition
  • Functional genomics
  • Transcriptome sequencing
  • Data Assembly
  • Data analyses

Staff contacts: