Silvia Melgar APEX

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Silvia Melgar

Silvia Melgar, PhD, is an APC Faculty Investigator under the Host – Microbe Dialogue Research theme in the APC Microbiome Institute, University College Cork (UCC), Ireland. She received her PhD in Immunology from Umeå University in Sweden, followed by a post-doctoral fellowship and a Senior Research Scientist position at AstraZeneca R&D Mölndal, Sweden and a Principal scientist position under the GlaxoSmithKline-APC collaboration, Cork, Ireland. Dr Melgar’ s research interests include the elucidation of mechanisms regulated by environmental factors such as diets and bacteria on host immune responses in human health and disease including Inflammatory Bowel Disease (IBD), colitis-associated cancer and colon cancer.

CURRENT POSITION
Senior Research Co-ordinator

CAREER PROFILE
Academic degrees
1995 BSc in Molecular Biology, Umeå University, Umeå, Sweden
2002 PhD in Immunology, Umeå University, Umeå, Sweden

Employment
2013 – present Senior Research Co-ordinator, APC Microbiome Institute, UCC, Ireland
2012 – 2013 Senior Research Fellow, Alimentary Pharmabiotic Centre, UCC, Ireland
2008 – 2012 Principal Scientist, GlaxoSmithKline, based in APC/UCC, Ireland
2005 – 2007 Senior Research Scientist AZ R&D, Sweden
2002 – 2005 Post-doctoral Research Fellow AstraZeneca (AZ) R&D, Sweden
1995 – 2002 PhD student, Dept Immunology, Umeå University, Umeå, Sweden

RESEARCH INTERESTS
•To identify novel molecular mechanisms associated to host and bacteria interactions and their relevance to intestinal disorders such as inflammatory bowel disease (IBD), colorectal cancer and in health.
•To study the interaction between the immune system, environmental stimuli (such as diets) and the microbiota in intestinal health and disease development in experimental models of inflammation and its translation to human diseases.
•Pre-clinical evaluation in animal models and in in vitro cell systems of novel therapies for inflammatory and malignant conditions in the gastrointestinal tract.

PUBLICATIONS
https://orcid.org/0000-0001-7463-3343

H-INDEX: 18 (ISI Web) / 26 (Google Scholar)
i10-INDEX : 42 (Google Scholar)
Total Publications – 51; Peer-Review Articles – 42; Reviews – 9; Editorial – 1; Book chapter – 1

Contact details: E-mail: S.Melgar@ucc.ie